Medicines We Can Trust Campaign Rallies Mekong Governments and Leaders to Improve Access to Quality Medicines
PHNOM PENH, 7 November 2018 – Cambodian Prime Minister Hun Sen and other leaders from the Greater Mekong Subregion joined hands as part of a global campaign to improve access to quality medicines. The announcement was made during the Phnom Penh Regional Conference on the fight against falsified, substandard and unlicensed medical products.
The Medicines We Can Trust campaign is a global movement advocating for access to quality medicines and stronger health regulatory systems.
“The world wastes approximately US$30 billion each year on poor-quality medicines,” said Dr. Phillip Nguyen, Director, International Regulatory Policy & Programs, USP, a committed partner of the campaign. “Substandard and falsified medicines give patients false hope, erodes trust in health systems and fail to protect people from the devastating impact of diseases. Despite the scale of this issue, it is rarely prioritized – or even discussed outside of expert circles. The Medicines We Can Trust initiative is a multi-stakeholder effort focused on raising awareness on the impact of poor-quality medicines on peoples’ lives.”
At least one in 10 medicines are copied illegally with substandard manufacturing practices in low- and middle-income countries, including many countries in Asia Pacific. In Southeast Asia alone, an estimated 30% of antimalarial drugs are of poor-quality contributing to an alarming rise in antimalarial resistance across the region. Anti malarials is just one of a broader range of drugs that are becoming in-effective; antimicrobial resistance already accounts for 700,000 deaths every year, could cause up to 10 million deaths per year, and cost US$100 trillion by 2050.
“In the Greater Mekong Subregion, cross-border collaboration between countries will be critical to stop the ongoing distribution of poor-quality medicines through trade channels. Cambodia’s leadership in convening a regional and multisectoral meeting to address the issue is a great start,” said Ruby Shang, Chair of the Asia Pacific Leaders’ Malaria Alliance (APLMA) Board.
“Momentum is building. Apart from the Cambodia conference, positive leadership on this issue is evident through existing platforms like Medicine Quality & Global Health conference, and Regional Regulatory Partnership (RRP). This global campaign will further strengthen this leadership as it engages the regional community, including policymakers, civil society, regulators, health professionals, and researchers to act against substandard and falsified medicines.” added Dr. Sivong Sengaloundeth, Deputy Director General, Food and Drug Department, Ministry of Health, Lao PDR.
“Ensuring that all people can access quality medicines to effectively fight infectious diseases is crucial. Unitaid is proud to support the campaign against poor-quality medicines to tackle the growing threat of antimicrobial resistance,” said Dr. Philippe Duneton, Unitaid’s Deputy Executive Director. “These superbugs are threatening the global health community’s gains against HIV, tuberculosis and malaria and jeopardizing the achievement of the Sustainable Development Goals.” Unitaid invests half of its portfolio – US$ 500 million – in innovative grants to combat drug resistance and is a committed partner of the campaign.
Visit Medicines We Can Trust to get involved and learn more. #MedsWeCanTrust
Lancet commentary highlights Unitaid interest in long-acting technologies to treat diseases
GENEVA – Unitaid is working with partners and stakeholders to explore introduction of long -acting (LA) technologies – such as injectable drugs, patches and implants – to treat infectious diseases in low and middle-income counties (LMICs), according to a commentary co-authored by Unitaid’s Executive Director Lelio Marmora and published in the Lancet.
“To avoid the pitfalls of the past, when new medicines were introduced first in high-income countries and only much later in LMICs, we need to be thinking ahead about LA technologies for infectious diseases,” said the article, co-authored by Carmen Perez Casas, Ian Grubb, Craig McClure and Marmora.
A global technical consultation will be held in Geneva on 1-2 November to consider the science and market landscapes for LA technologies.
Scientific and technological advances may make it possible over the next decade for children to be protected from malaria for an entire season with a single injection of chemoprophylaxis, for example, or for women to protect themselves from being infected with HIV by taking capsules once a fortnight that slowly release antiretroviral medicine.
The article cited Cabotegravir, a new antiretroviral drug, that is being studied as a singular intramuscular injection every eight weeks for pre-exposure prophylaxis, as well as LA formulations in malaria that are being explored for chemoprophylaxis and vector control.
Apart from injectable drugs, once-weekly gastric resident capsules, various types of patches, implants and vaginal rings were also being developed to deliver long-acting medicines, the article said.
Long-acting technologies are likely to pose big challenges in low and middle-income countries and will require stronger health systems in managing supply chains and medical waste.
Difficult intellectual property and generic manufacturing issues will also have to be sorted out before the completion of clinical trials, if LA products are to be sourced from generic suppliers, as is the case with more than 90 percent of antiretroviral drugs supplied by funders such as the Global Fund and the US President’s Emergency Plan for AIDS Relief (PEPFAR), the article added.
“Above all, LA approaches in addition to being safe must be designed upfront for simplicity to minimize burden and increase convenience for patients, providers and health services.” Please click here to read the commentary in full.